I received three mails for my question on "linkage analysis". Before
I got these mails I had thought linkage analysis is one of the
mathematical techniques to determine the gene location. Now I know
that it has a rather general meaning. At any rate, I made a list of
introductory literatures.
[Summary of literatures on Linkage Analysis]
[1] Ray White and Jean-Marc Lalouel : Chromosome Mapping with DNA Markers,
Scientific American, February, 1988 (Vol. 258, # 2)
(An excellent start on the general topic of "linkage analysis")
[2] Jurg Ott : Analysis of Human Genetic Linkage,
Johns Hopkins Univ. Press (1985, 1991)
(For a discussion of linkage analysis of simple mendelian
traits in humans)
[3] Botstein, D.,R.L. White, M. Skolnick, and R.W. Davis :
Construction of a genetic linkage map in man using restriction
fragment length polymorphisms, Amer. J. Human Genetics. 32:314, 1980.
[4] Sturtevant : Journal of Experimental Zoology vol. 14 pp. 43-59.
(This article was the earliest important paper and has been
reprinted in several books of collected important papers).
I was told that there were a few postings for me in this news group,
bionet.molbio.gene-linkage, but unfortunately I could not find them
now. I think they have been expired from our news spool. I will
appreciate it very much if some one could mail them.
Thank you very much and a Merry Christmas!
--
Michio Nakanishi <naka at ics.osaka-u.ac.jp>
