The Science Advisory Board's latest study, "The Tools & Techniques of
Protein Science" is providing unique insights into the most current
areas of investigation in protein and proteomic research. More than
700 Science Advisory Board members have already participated in the
first stage of the eight-part examination of protein science now
being conducted online at www.scienceboard.net.
Although the study is still ongoing, early results indicate that the
primary research objective of the majority of these scientists is to
identify and/or characterize protein-protein or peptide-protein
interactions. Most of this research is conducted with human-, mouse-
and rat-derived proteins, and scientists use both recombinant and
non-recombinant sources of these proteins but prefer recombinant
protein. There is also a preference for using tagged proteins over
untagged proteins. Antibodies are the most common class of proteins
that is studied followed by membrane proteins and then signal
transduction proteins and kinases.
The top two cutting-edge proteomics technologies that these
scientists are considering using are protein chips and liquid-phase
separation techniques (other than 2D gel electrophoresis). Academic
scientists would like the life sciences industry to focus on
improving current separation and detection methods that would enable
them to analyze closer to 100% of the proteome. In contrast,
industrial scientists would like the life sciences industry to focus
on automating all procedures in order to achieve improved
reproducibility and higher throughput.
Upcoming studies include Protein visualization, Protein interactions
and Protein Identification and Characterization.
The Science Advisory Board is an online panel of more than 5,000
scientists, physicians and other life science and medical
professionals from 62 countries. By convening electronically,
Science Advisory Board members participate in online studies to voice
their opinions on issues that directly affect the evolution and
development of the tools and techniques of their professions.
If you are interested in contributing your own opinions on the tools
and techniques of protein science or participating in other studies
that may be of interest to you, please register at The Science
Advisory Board website at www.scienceboard.net or you may contact
Molly Scott, Membership Coordinator, at m.scott at scienceboard.net for
membership information and study details. Your identity and personal
information will be held in the strictest confidence, and you will
receive compensation for any studies in which you choose to
The Science Advisory Board
"Expert Insights from Gene to Drug"
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