IUBio Biosequences .. Software .. Molbio soft .. Network News .. FTP

drivers & responders in muscle tissue

sandra-schulze at uiowa.edu sandra-schulze at uiowa.edu
Wed Nov 12 13:02:22 EST 2003

Hi there Drosophila community!

I have three questions:

First of all, I'd like to find GAL4 drivers that are active in adult 
structures - especially muscle tissue (indirect flight muscle for instance).

Secondly I'd like to knock out specific muscle cells/blocks in either larvae or 
adults, in order to see if a specific muscle destroyer phenocopies mutants I am 
testing.  An apoptosis promoter might do the trick, and some are available from 
Bloomington, but I have heard/read somewhere that not all apoptosis promoters 
are equivalent-some seem to have to be used in combination to have any effect, 
and some effects are not cell autonomous.  Clearly i am not an apoptosis 

Thirdly i have read/heard/imagined that there are muscle drivers that drive in  
selected subsets of muscles. This seems like a wonderful system, with an in-
built control. 

If anyone out there can provide me with any information on the above, I'd be 
most grateful. 

Many Thanks, 

Sandra Schulze


More information about the Dros mailing list

Send comments to us at biosci-help [At] net.bio.net