Starting January 2002
Department of Biochemistry and Biophysics
Texas A&M University, College Station, TX
Motivated researchers with experience in Molecular Biology and/or
Biochemistry and/or Drosophila Genetics are sought.
* With the student population of over 40,000, Texas A&M is an
outstanding University located in the vicinity of Houston, TX.
* Texas A&M is one of the biggest and well-funded Universities in
America; TAMU is famous for its Engineering and Life Sciences research
all over the world.
* Dr. Vlad Panin is currently staffing the newly created laboratory.
* Specialty of the laboratory is the highly competitive and cutting-edge
field of Developmental Biology.
* Ample opportunities for professional growth and independent research
projects are available.
Developmental Biology / Glycosylation and Cell Interactions
Extracellular domains of proteins are often glycosylated, i.e. modified
by covalently attached carbohydrate chains. These carbohydrate
modifications can significantly affect molecular interactions
influencing cell adhesion and signaling processes. The principal
research interest of our laboratory lies at the intersection of
Developmental and Cell Biology with the field of Glycobiology, and it is
focused on elucidation of the role of glycosylation in developmental
events and cell interactions. We are using the Drosophila model system,
known for its powerful molecular genetics, in combination with advanced
biochemical and cell biological approaches.
Moloney, D. J., Panin, V. M., Johnston, S. H., Chen, J., Shao, L.,
Wilson, R., Wang, Y., Stanley, P., Irvine, K. D., Haltiwanger, R. S.,
and Vogt, T. F. (2000) Fringe is a glycosyltransferase that modifies
Notch. Nature. 406: 369-375.
Panin, V. M. and Irvine, K. D. Modulators of Notch signaling (1998)
Semin. Cell. Dev. Biol. 9: 609-617.
Papayannopoulos, V., Tomlinson, A., Panin, V. M., Rauskolb, C., and
Irvine, K. D. (1998) Dorsal-ventral signaling in the Drosophila eye.
Science 281: 2031-2034
Panin, V. M., Papayannopoulos, V., Wilson, R., and Irvine, K.D.(1997)
Fringe modulates Notch-ligand interactions. Nature. 387: 908-913.
Contact: Dr. Vlad Panin
Waksman Institute, Rutgers University
Tel. (732) 445-2872 FAX (732) 445-5735
e-mail: panine at waksman.rutgers.edu
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