I have an ENU-induced dominant uncoordinated mutation I would like to
find a home for! It maps recombinationally to 2-42; this is roughly
salivary division 31. Development of heterozygotes is little if any
delayed, but adults have difficulty eclosing; keeping the culture
at low humidity helps here, as does turning the vial upside down.
Newly-eclosed adults move very slowly, though they do manage to do
all the fly-type motions (grooming, etc) except flight, which they do
not attempt. Movement seems to improve with age. Females are quite
fertile; males seem to be sterile, even with their uncoordinated
sisters. The few balancers I have tried seem to make the flies just
that little bit too sick, so I am keeping this stock in a wild-type
background by shaking the Uncs down onto the cotton, dumping them
onto my counting plate, and letting the wild-type sibs fly away.
This works, but it is labor- intensive and I have no interest in
this mutation! If you do, email me and I will mail you a copy.
I would like to get this mutation out to as many labs as might be
interested in it; it is difficult to keep, and once I am sure that
others have a going culture I am *not* going to keep my stock going.
Just in case you're wondering: the parental male was mosaic
-- he was wild-type in
movement but all his mutagenized-second progeny were Unc. And I
noticed that because I was scoring for Cy[+] through the vial
Everyone who is interested, let me know *soon*!
Adelaide TC Carpenter atc12 at mole.bio.cam.ac.uk