We are working on a bioengineering project with Chlamydomonas and are
experiencing problems with cells irreversibly adsorbing to glass surfaces (both
native and oxidized). Preliminary experiments suggest that hydrophobic
polymers such as poly(dimethylsiloxane) might be useful in resisting the
adsorption of cells - however before going to lengths to investigate
appropriate surface chemistries - it seems prudent to contact the newsgroup and
inquire if anyone is aware of commonly used tricks for treating glass slides
(silylation for example). In our application, the material must be optically
transparent for the sake of microscopy.
Any information would be very much appreciated.