POSTDOCTORAL/RESEARCH ASSOCIATE POSITION
MOLECULAR GENETIC ANALYSIS OF CHLAMYDOMONAS FLAGELLAR DYNEIN
GEORGE WITMAN LABORATORY
An NIH-supported postdoctoral position will be available beginning
around January 1, 1996, for the study of Chlamydomonas outer arm dynein using
a combination of genetic, molecular genetic, and cell biological approaches.
The project involves insertional mutagenesis followed by the cloning and
characterization of tagged genes that are essential for assembly of the outer
arm dynein onto the flagellar axoneme. Extensive use will be made of
procedures for transformation of the nuclear genome. This project is expected
to identify the docking proteins that specify the dynein binding site on
flagellar doublet microtubules, as well as new gene products that are involved
in targeting dynein to the correct cell organelle. Previous experience with
molecular genetic techniques is desirable.
The Worcester Foundation for Biomedical Research is a private, non-
profit research institute located on a beautiful 75-acre campus in suburban
Shrewsbury, 3 miles from Worcester and approximately 35 miles from Cambridge
and Boston. The Foundation offers excellent facilities and an exceptionally
stimulating environment for postdoctoral study.
Interested persons should contact George Witman by phone (508-842-8921
ex. 344), fax (508-842-3915), e-mail (Witman at SCI.WFBR.EDU) or mail at
Worcester Foundation for Biomedical Research, 222 Maple Avenue, Shrewsbury, MA