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Guy Perriere perriere at biomserv.univ-lyon1.fr
Thu Dec 9 11:17:22 EST 1999

                    HOBACGEN Release 6 (December 1999)

     The  new  release  of  HOBACGEN  (the Homologous Bacterial Genes
     Database)  is  now available. Information on the database can be
     accessed at:


     HOBACGEN  is  a  database  system  that contains all the protein
     sequences of bacteria  organized into families. It allows one to
     select  sets  of  homologous genes from bacterial species and to
     visualize  multiple  alignments  and  phylogenetic  trees.  Thus
     HOBACGEN is particularly useful for comparative genomics, phylo-
     geny and molecular evolution studies on bacteria.

     The  database contains all sequences of bacteria (eubacteria and
     archeae)  and  yeast  taken  from SWISS-PROT + TrEMBL, with some
     annotation modifications. It contains also all the corresponding
     nucleotide  sequences  from  EMBL. Homologous proteins are clas-
     sified  into  families  and multiple alignments and phylogenetic
     trees are computed for each family.

     This new version of HOBACGEN has been built using sequences from
     SWISS-PROT  38  (+ updates)  and  TrEMBL  12.  Among the 109,077
     proteins used to build this release, 85,059 are from eubacteria,
     14,998 from archaea, and 6,873 from yeast.

     If  you  use  HOBACGEN  in  a  published  work,  please cite the
     following reference:

     Perriere,  G.,  and  Duret,  L.  (1999)  HOBACGEN:  database  of
     homologous  genes  in  bacteria.  In  Proceedings  of the German
     Conference  on  Bioinformatics,  Giegerich, R. (ed.), Bielefield
     University, Bielefield, pp. 167-173.

                  Guy Perriere and Laurent Duret
                  Laboratoire de Biometrie et Biologie
                  Evolutive - UMR CNRS 5558
                  Universite Claude Bernard - Lyon 1
                  43, bd. du 11 Novembre 1918
                  69622 Villeurbanne Cedex

                  Email: {perriere, duret}@biomserv.univ-lyon1.fr

Guy Perriere - Laboratoire BBE - Universite Claude Bernard Lyon 1
  43, bd du 11 Novembre 1918 - 69622 Villeurbanne Cedex - France

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