IBC's International Conference on Display Technologies
In Protein Engineering, Drug Discovery, Molecular Evolution and
February 10-11, 1997 * Caesars Tahoe Hotel and Casino * Lake Tahoe, NV
* Small molecule drugs from phage * Vaccine developments * Protease
inhibitors * High affinity agonists and antagonists * bFGF inhibitors
* IL-1 receptor antagonists * Kunitz domain inhibitors of serine
proteases * Structure/function analysis * Disease-specific epitopes
Alternate Display Technologies
* Phage and bacterial library crossing *FLITRX * Novel biological
diversity systems * Filamentous phage selection * Eukaryotic virus
* Orphan sites * Genomics * Selection by catalytic activity * In vivo
systems * BNP analogs
* Phage and bioinformatics * In vivo panning * Protein-protein
interactions * Rebuilding proteins by size reduction * Screening of
cDNA expression libraries * Modified receptor interactions * Protein
IBC gratefully acknowledges Jill Winter of Chiron Corporation for her
assistance as a scientific advisor for this meeting.
Complimentary book to the first 50 paid, registered delegates!
Phage Display of Peptides and Proteins is an insightful step-by-step
discussion of phage display protocols for preparing affinity reagents,
monoclonal antibodies and evolved proteins. Both novices and experts
will benefit from this book which outlines strategies for maximizing
the successful application of phage display technology to one's
research. Editors: Brian K. Kay, University of North Carolina, Jill
Winter, Chiron Corporation, John McCafferty, Cambridge Antibody
Technology. Complimentary copies will be given to the first 50 fully
paid, registered delegates of this meeting. Books may be picked up by
delegates during conference registration.
IBC USA Conferences, Inc.
225 Turnpike Road
Southborough, MA 01772-1749, U.S.A.
Tel: (508) 481-6400 * Fax: (508) 481-7911
E-mail: reg at ibcusa.com
Monday, February 10, 1997
8:00 Registration, Poster/Exhibit Set-Up, Coffee and Breakfast
Display Technologies in Peptide Optimization
9:00 Chairperson's Welcome and Opening Remarks
Riccardo Cortese, M.D., Ph.D., Scientific and Managing Director, IRBM,
9:15 Discovering Orphan Sites on Multifunctional Proteins by
Steve Rosenberg, Ph.D., Senior Director of Biological Chemistry,
9:45 Defining Peptide Binding Motif for MHC Class I Molecules
Using Phage Display and Artificial Neural Networks
Michael P. Jackson, Ph.D., Director, RW Johnson Pharmaceutical
10:15 Poster/Exhibit Viewing and Refreshment Break
11:00 Selection Of Disease-Specific Epitopes Using Serum Samples
and Phage Displayed Libraries
Riccardo Cortese, M.D., Ph.D.
11:30 A Library of Organic Landscapes on Filamentous Phage
Valery A. Petrenko, Ph.D., Research Professor, University of Missouri
Display Technologies in Protein Libraries and Protein Optimization
1:15 Chairperson's Remarks
Jane Osbourn, Ph.D., Senior Scientist, Cambridge Antibody Technology,
1:30 Functional Analysis and Engineering of Heregulin Using
Marcus D. Ballinger, Ph.D., Postdoctoral Fellow, Genentech, Inc.
2:00 Exploiting the Diversity of Large Phage Libraries
Jane Osbourn, Ph.D.
2:30 Phage Display and Activation of a Zymogen
Laurent S. Jespers, Ph.D., Senior Scientist, Center for Transgene
Technology and Gene Therapy, Flanders Interuniversity Institute for
3:00 Poster/Exhibit Viewing and Refreshment Break
3:45 Selection of BNP Analogs that Have Modified Natriuretic
Peptide Receptor Interactions
Lisa J. Garrard, Ph.D., Senior Scientist, Scios, Inc.
4:15 The Design of Potent and Specific Kunitz Domain Inhibitors
of Serine Proteases: Utilization of Phage Display and Competitive
Mark S. Dennis, Senior Research Associate, Genentech, Inc.
4:45 Custom Affinity Ligands from Phage Display for Large-Scale
Charles Arthur Ley, Ph.D., Director of Research, Dyax Corporation
5:15 Close of Day One
Tuesday, February 11, 1997
7:30 Poster/Exhibit Viewing, Coffee and Breakfast Bakeries
Alternate Display Technologies
8:15 Chairperson's Remarks
Andreas Pluckthun, Ph.D., Professor of Biochemistry, University of
8:30 Selectively Infective Phage (SIP)
Andreas Pluckthun, Ph.D.
9:00 The FLITRX E. coli Random Peptide Library
Brian C. Tripp, Ph.\D., Postdoctoral Research Fellow, Genetics
9:30 Combining Bacterial and Phage Display for Potential Gene
Carl Borrebaeck, D.Sc., Professor, Lund University, Sweden
10:00 Poster/Exhibit Viewing and Refreshment Break
10:45 Eukaryotic Virus Display
Ian Jones, Ph.D., Group Leader, Institute of Virology and
Environmental Microbiology, UK
>From Libraries to Drugs
11:15 Chairperson's Remarks
Brian K. Kay, Ph.D., Associate Professor, University of North Carolina
11:30 Use of Recombinant Peptide Libraries to Identify High
Affinity IL-1R Type I Antagonists
Stephen Yanofsky, Ph.D., Senior Scientist, Molecular Pharmacology,
Affymax Research Institute
12:00 Use of Phage Libraries of Long Peptides in Drug Discovery
Wlodek Mandecki, Ph.D., Director, Molecular Immunology, DGI
12:30 Lunch on your own
1:45 Peptide Inhibitors of Basic FGF
David Israel, Ph.D., Director of Cell Biology, Pharmaceutical
2:15 Cloning Novel Genes with Phage-Displayed Peptide Ligands
Brian K. Kay, Ph.D.
2:45 Searching for Magic Bullets from Peptide Libraries
Erkki Ruoslahti, M.D., President and CEO, The Burnham Institute
3:15 Poster/Exhibit Viewing and Refreshment Break
3:45 The Use of Peptides as Informants in the Design of Novel
Vaccines and Drugs
Peter Laing, Ph.D., Director of Research, Peptide Therapeutics, United
4:15 Small Molecule Drugs from Phage Display Selected Proteins
Robert Charles Ladner, Ph.D., Chief Scientific Officer and Senior Vice
President, Dyax Corp.
4:45 Human cDNA Phage Display: A New System for Discovering Drug
Allan Peng, Ph.D., President, GeneMax, Inc.
5:15 Close of Conference