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Mycoplasma Genitalium analysis

Georg Casari Georg.Casari at EMBL-Heidelberg.de
Sat Nov 18 15:41:00 EST 1995


The complete results of the automatic GeneQuiz annotations are available
through WWW through :


 The first two completely sequenced genomes of self replicating
organisms have been determined and made publically available by TIGR
(http://www.TIGR.ORG/ ).
 For the first time it is possible to study complete repertoires of
protein genes in a simple organism and to compare them. The two genomes
presently analysed by GeneQuiz are:

Haemophilus influenzae (Science 269:496-512, 1995) and 
Mycoplasma genitalium  (Science 270: 397-403, 1995)

All open reading frames (= predicted protein sequences) provided by
TIGR have been analysed by GeneQuiz and the results are available
through www. The Analysis of Haemophilus influenzae is currently
updated and will replace the previous ones within the next couple of
days, taking into account thousands of new protein sequences and
hundreds of new protein 3D-structures.

The server ( http://www.sander.embl-heidelberg.de/genequiz/ ) reports
the predicted function, number of homologues, reliable homologies with
proteins of known 3D-structure and other sequence features.  The level
of confidence in functional predictions is classified in reliability
levels. In order to make access more efficient the server provides
access to those data by simple queries.

An aim of GeneQuiz is to provide an uniform interface to all genomes
incorporated in the GeneQuiz databases. Other genomes will enter as
soon as they become available. This uniform view will facilitate
comparisons between genomes coming from various sources.

Georg Casari
EMBL, Meyerhofstr 1, D69012- Heidelberg; Germany
Tel:    (+49) 6221 - 387 472        Fax:  (+49) 6221 - 387 517
E-mail: casari at EMBL-Heidelberg.de   www:  http://www.embl-heidelberg.de/~casari

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