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DNA with trinucleotide expansions

jeanne beck jeanne_beck at cimr.umdnj.edu
Wed May 10 18:54:47 EST 1995


DNA WITH CHARACTERIZED 
TRINUCLEOTIDE EXPANSIONS
    
    DNA samples with characterized trinucleotide expansions are
available from patients with Huntington disease (HD) and myotonic
dystrophy (DM), as well as >From patients and unaffected carriers of
fragile X syndrome (FRAXA). The expanded CAG repeats in the HD alleles
of affected individuals range from 44 to 70. The degree of
amplification of the CTG repeat is also available for individuals with
DM. In addition, expansions in the CGG repeat in the FMR1 gene have
been determined in individuals transmitting or expressing fragile X
syndrome. These materials are being distributed by the National
Institute for General Medical Sciences' (NIGMS) Human Genetic Mutant
Cell Repository. For additional information or a printed catalog,
please contact:
    The NIGMS Human Genetic Mutant Cell Repository
    Coriell Cell Repositories
    Coriell Institute for Medical Research
    401 Haddon Avenue
    Camden, New Jersey 08103
Telephone:  (800)-752-3805, in the United States
            (609)-757-4849, outside of the United States
Fax:        (609)-757-9737



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