In Article <1774B9FD1S85.60057923 at wsuvm1.csc.wsu.edu>,
60057923 at wsuvm1.csc.wsu.edu(GS Fraley) wrote:
>MHC. So differeing MHC may be revealed in mate selection I cannot see how
>it is causal. If for no other reason then I cannot see how a potential mate's
>MHC is getting from her to my nose. Pheromones..yes, perfume...yes, but a
>membrane bound MHC molecule??
>
indeed, mhc has long been implicated in sexual selection and mating
phenotypes-at least in rodents. apparently it is a peptide related
phenomena, just as mhc is thought to normally function. the membrane bound
mhc molecule "receives" the peptide and somehow transmits a signal.
normally mhc works in context with tcr/peptide/mhc, with mhc presenting the
peptide, so i am not sure what the proposed mechanism for signaling is. i
believe that if you research boyse, e., (odor/mhc research) you will find
references accordingly.
regards, ralph
R.M. Bernstein
Dept of Micro/Immuno
University of Arizona
Ph: 602 626 2585
Fx: 602 626 2100
url: http://lamprey.medmicro.arizona.eduhttp://radon.gas.uug.arizona.edu/~bernster
