In article <2gb0u7INNc5b at network.ucsd.edu>, root at ballison.extern.ucsd.edu (Administrator) writes:
> I was wondering if anyone knew exactly why a cell chooses
>one gene over another in dominant genes (in some cases co-dominance).
>Is there a specific nucleotide sequence in the DNA that tells if a gene/trait
>is to be dominant or recessive? [...]
>--
>Ryan | "A fanatic is one who can't change
>Univ of Calif, San Diego | his mind and won't change the
>root at ballison.extern.ucsd.edu | subject." -- Winston Churchill
Dominant diseases are caused by the presence of (almost always) a single
mutational change which causes a loss of function or gain/modification of
function. There are multiple different mechanisms by which mutations
cause domiant diseases (many occur when mutant protein forms complexes
with either the remaining normal allele or with different proteins).
Recessives diseases result when the remaining normal allele is sufficient
to provide enough protein for the cell/organism to survive.
Darrell O. Ricke E-Mail: RICKE at RCF.MAYO.EDU
