In Message Mon, 8 Jun 92 13:01:57 -0500,
danj at welchgate.welch.jhu.edu (Dan Jacobson x-8453) writes:
>>Richard Williams asks:
>>>Does anyone know if there are any databases of DNA/protein 'motifs' on
>>the net that I can use to screen sequences for regions of homology with known
>>functional motifs? (- e.g. To scan a protein sequence for potential RNA
>>binding regions). I don't need overall sequence comparison/alignment, but
>>rather a tool to pick out potential regions of interest in sequences of poorly
>>defined function.
>>For protein motifs there is PROSITE which can be obatained by anonymous ftp from
>(among other places) ncbi.nlm.nih.gov in the repository/prosite directory.
>There are two programs which can be used to scan sequences with this database.
>>For Unix and Vax/VMS boxes there is prosearch which can be obtained from
>(among other places) ftp.bio.indiana.edu in the molbio/search directory.
>Prosearch is being phased out for PCs.
>>For Macs there is Macpattern which is available by anonymous ftp from (among
>other places) ra.nrl.navy.mil in the MacSciTech/biology directory.
>>Kudos to the authors and the ftp sites.
>>Best of luck,
>>Dan Jacobson
>>danj at welchgate.welch.jhu.edu
Why is Prosearch for PC systems being phased out? Is the nature of the
database such that the "old" phased-out PC version of Prosearch will not
work with future updates of the PROSITE database?
Thanks,
An feeling abandoned PC user....
Richard Timmer
Dept. of Chem. and Biochem. (phone) 512-471-4562
The Univ. of Texas at Austin (fax) 512-471-8696
Austin, TX 78712 (e-mail) timmer at ccwf.cc.utexas.edu