Regulation of pathogen defense by epigenetic mechanisms and by miRNAs
A postdoctoral position is immediately available in the laboratory of Dr. Ramesh Raina at Syracuse University to participate in one or more of the ongoing research projects focusing on understanding the molecular mechanisms regulating pathogen defense in Arabidopsis. The first project involves understanding epigenetic mechanisms regulating pathogen defenses. We have recently identified and characterized an Arabidopsis histone demethylase that is required for defense against pathogens. This project will involve detailed characterization of this protein and identification of downstream targets of this protein by ChIP analysis, and characterization of role of additional members of this family in pathogen defense and other stresses. The second project involves understanding regulation of pathogen defense by miRNAs. We have recently identified a novel miRNA that is strongly induced in response to avirulent bacterial pathogens. This project involves detailed characterization of this miRNA including regulation of its expression, biogenesis and role in pathogen defense.
This position is available for 3 years. Candidate should have a Ph.D. in molecular biology, genetics, biochemistry or a related discipline. Experience with ChIP analysis and/or next generation sequencing is desirable. The successful candidate must be able to independently design and conduct experiments, and willing to work collaboratively with other members of the laboratory.
Interested individuals should submit a CV, a statement of research experience and interests, and name and contact information of three referees as a SINGLE PDF file to raraina from syr.edu<mailto:raraina from syr.edu> .
Syracuse University is an equal opportunity/affirmative action employer.
Ramesh Raina, Ph.D.
Department of Biology
Syracuse, NY 13244 USA
Tel: 315-443-4546 (office)
Tel: 315-443-4750 (lab)