A postdoctoral fellow position is available at the Institute of Plant
and Microbial Biology, Academia Sinica (IPMB-AS), to study the role
of Polycomb Group proteins in plant (broccoli) development, a
collaborative effort between Dr. Z. Renee Sung, UC Berkeley,
California and Dr. L. Oliver Chen in IPMB-AS, Taiwan. Polycomb group
proteins play major roles in embryogenesis, cancer and stem cell
renewal. They encode chromatin proteins that form multi-protein
complexes, functioning to maintain gene silencing via histone
modifications. In Arabidopsis, PcG proteins are required to regulate
major developmental processes such as seed development and flowering.
Dr. Sung's laboratory has been studying the molecular mechanism of
PcG proteins in silencing flower MADS-box genes and maintain
vegetative development. Dr. Chen's laboratory focuses on transgenics
and functional gene analyses on broccoli (Brassica oleracea. Var.
italica) The collaborative project investigates the role of PcG
proteins in broccoli development with 2 emphases-- the evolution of
PcG protein genes and the isolation of the PcG protein complexes.
Despite the importance of the PcG protein genes in Arabidopsis
development, little is known of the role of these genes in other
plant species. Broccoli, being a close relative of Arabidopsis, is
an ideal organism for investigating the functional conservation of
these genes during evolution. Moreover, tools developed in
Arabidopsis can be readily applied to broccoli. Due to its large
plant size, broccoli is also excellent for protein purification and
protein complex isolation studies.
Candidates should have a PhD and experiences in plant molecular
biology and protein biochemistry with skills in gene cloning, DNA and
RNA analysis, protein purification, immunoprecipitation, western
analysis. Experiences in Chromatin immunoprecipitation, microarray,
transgenic plants and plant genetic analyses are desirable.
Reasonable levels of writing and verbal communicating skills in
English are required. Successful applicants will be one who is
capable of independent research and experimental designs. A
self-motivated, creative individual with communication skills are
required. The appointee will lead a small group of Chinese graduates
and research assistants. For additional information, candidate should
access Dr. Sung's website through the Department of Plant and
Microbial Biology, UC Berkeley, http://pmb.berkeley.edu, and Dr.
Chen's website through the Institute of Plant and Microbial Biology,
Academia Sinica, http://ipmb.sinica.edu.tw.
The salary will be between US$1,700.00~2,600.00 per month depending
on experience. The positions can start as early as February 2008.
IPMB-AS is well-equipped with five nice core facilities for cell
biology, microarray analysis, proteomics, transgenic plant generation
and bioinformatics studies. For your interest, you are welcome to
visit our web site as indicated previously. There are seven other
Life Science Research Centers or Institutes -- Institutes of
Molecular Biology, Biological Chemistry, Biomedical Sciences,
Cellular and Organismic Biology and Genomic Research Center,
Agricultural Biotechnology Research Center and Research Center for
Biodiversity all in the walking distance providing an excellent
research environment for collaborative studies. Rental apartments and
housings are available in the neighborhood. Minimal level of living
costs is around US$700.00~800.00/month. Convenient transportation
system to downtown Taipei as well as travel around the island is also
available. If you have any other question, please contact us at
zrsung from nature, or ochenlf from gate.sinica.edu.tw