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postdoc offer

Nobody nobody at hgmp.mrc.ac.uk
Tue Oct 22 07:31:42 EST 2002

Postdoc position offer

A postdoc position is available in the team of Stephane Blanc of the 
INRA Research Station of Comparative Pathology, located at Saint 
Christol-lez-Ales in Southern France. The team's research focuses on 
transmission of cauliflower mosaic virus (CaMV) and uses molecular 
biological, cell biological and structural biological approaches to 
uncover the mechanisms, regulation, and evolution of CaMV 
transmission by its aphid vector.
Among our projects are the determination of the mutation and 
recombination rate of CaMV. Both mutation and recombination frequency 
appear to be extremely high in CaMV populations, even after one 
single cycle of infection of a host plant. From these frequency data, 
in order to calculate the mutation and the recombination rate, it is 
crucial to precisely determine the kinetics and the rate of the 
replication cycle of CaMV, two parameters not known for any plant 
We are looking for a postdoc ready to tackle this question by 
infecting protoplasts with wild type and replicase-deficient CaMV in 
order to find out the duration of the replication cycle of CaMV. 
Quantitative PCR, Immunodetection, and electron microscopy to detect 
and quantify progeny virus particles are some of the methods to be 
used. The experiments will be complemented by in vivo studies of 
plants agroinfiltrated or inoculated with CaMV. In addition to 
classical cell biology and molecular biology skills, experience in 
protoplasts preparation would be most appreciated.

The applicants must be under 35 and citizen of a NON-European Union 
country. Young researchers already in a French lab are not eligible.

This postdoc position is available as of 1 December 2002 and until 
January 2003. Initial funding is for one year with the possibility to 
prolong for another two years. The yearly salary is about 22.200 =A4 
net depending on the status of the candidate.
=46or all further information, please contact Stephane Blanc at Station 
de Recherches de Pathologie Comparee INRA-CNRS-UMII, 30380 St. 
Christol-lez-Ales, France,
e-mail blanc at ensam.inra.fr
tel. +33 4 66 78 37 15, fax +33 4 66 52 46 99.

DEAD-LINE for receiving application is the 1 November 2002

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