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Postdoc on Ubiquitin/26S Proteasome

Rick Vierstra vierstra at facstaff.wisc.edu
Wed May 5 12:02:25 EST 1999


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<font size=4>Postdoctoral Position&nbsp; Ubiquitin/26S Proteasome<br>
University of Wisconsin-Madison <br>
Richard D. Vierstra<br>
<br>
Position is available immediately to study the biochemistry, molecular
biology, and/or genetics of the ubiquitin/26S proteasome-dependent
proteolytic pathway in plants with a emphasis on Arabidopsis thaliana
[see Vierstra, R.D. (1996) Plant Molec Biol. 32: 275302 for
review].&nbsp; Accumulating molecular data indicate that the
ubiquitin/26S proteasome pathway represents a major regulatory mechanism
in Arabidopsis, involved in the cell cycle, numerous light and hormone
signaling pathways, development, and stress responses.&nbsp; We already
know over 100 Arabidopsis genes that participate making it one of the
most complex processes in the plant.<br>
<br>
The successful applicant will join a larger research group using a
variety of techniques to define the pathway's roles.&nbsp; A main focus
now is the analysis of a large collection of T-DNA insertional mutants in
various component of the pathway, some of which have profound effects on
Arabidopis growth and development. Through the analysis of these mutants,
we hope to define the specific roles of each component and to identify
important regulatory proteins that are targets.&nbsp;&nbsp; Experience in
molecular and biochemical techniques is necessary, but prior work with
plants is not required. <br>
<br>
The University of Wisconsin is a first class research university with one
of the largest groups of scientists focusing on biology in general, and
on Arabidopsis in particular.&nbsp; The Arabidopsis group is currently
funded by a 5-year NSF grant specifically to train scientists working on
this plant and hosts the International Arabidopsis Meeting, held on
campus every other year.&nbsp; The University is situated in Madison, the
capitol of Wisconsin and is routinely rated as &quot;one of the best
livable cities in America&quot;.&nbsp; The surrounding region supports a
wide array of both cultural and outdoor activities. <br>
<br>
Interested candidates should send or email a resume, description of
research experience, and the names of three references to:<br>
<br>
Dr. Richard D. Vierstra<br>
Cellular and Molecular Biology Program<br>
1575 Linden Drive<br>
University of Wisconsin-Madison, Madison, WI&nbsp; 53706.&nbsp; <br>
Phone (608) 262-8215<br>
fax (608) 262-4743<br>
email &quot;vierstra at facstaff.wisc.edu&quot;.<br>
<br>
If you have any questions do not hesitate to contact me at the above
addresses.<br>
<br>
</font><br>
<div>Dr. Richard D. Vierstra</div>
<div>Cellular and Molecular Biology Program</div>
<div>and Department of Horticulture</div>
<div>University of Wisconsin-Madison</div>
<div>Madison, WI&nbsp; 53706&nbsp; USA</div>
<div>608-262-8215</div>
<div>608-262-4743 fax</div>
vierstra at facstaff.wisc.edu
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