Ap3-1 is a temperature sensitive missense mutation that substitutes a
methionine for a lysine residue at the carboxyl end of the K-domain in
Ap3 gene. Ap3-11 is a suppressor of ap3-1. now, direct sequencing of
the ORF and most of the introns in ap3-11 show no mutation except the
original ap3-1 but ap3-11 mutants are closer to wild-type than to
does anyone know what's happening here?