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controversies and ethics

Wayne M. Barnes, Ph.D. barnes at BIODEC.WUSTL.EDU
Tue Jan 31 10:07:12 EST 1995

Dear Dr. Chaudhury,

     You're right, I should increase the initial fly-swatting selective 
pressure to a level that kills a noticeable percentage of them at each 

     I believe that the Bt resistance noticed so far in inadvertent field 
selections is not absolute; a higher level of Bt still kills the resistant 
strains.  I don't believe a single change is enough to cause absolute 
resistance, but if a few small changes are selected for at low levels of Bt 
application, eventually serious resistance could be selected, especially 
after the benefits of recombination add to this evolution.  

Wayne M. Barnes, Ph.D.            Biochemistry Dept. 8231
Washington University School of Medicine
660 South Euclid Ave, St. Louis, MO 63110             USA
314/362-3351   Barnes at biodec.wustl.edu  fax: 314/362-7183

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