Aubrey de Grey wrote:
>>> This is not to say that there is no selection of mutation-free oocytes
> between meiosis and ovulation, only that there is no need to postulate
> one based on current evidence.
I haven't had time to look up the references you suggested, but will soon,
thank you very much-you are an invaluable resource. Why do you say "between
meisosis and ovulation"? Why not during meiosis itself? I am thinking of a
mechanism similar to what has been observed in yeast ERCs (don't know if that
segregation mechanism has been understood).
>>> > Is there less mtDNA damage in post-ovulatory eggs than in other cells
> > in the same organism?
>> I don't know of any study of this. Getting enough such eggs to measure
> mtDNA mutations is probably difficult.
>
I guess one should do this with mice. By "other cells" I now mean
pre-ovulatory oocytes.
-Iuval
