Paul Brookes wrote:
> WRT the comments on CR and gene arrays, the whole idea that identifying
> genes changed in CR and then changing them by a pharmaco / genetic CR
> mimicry approach is more than a little shortsighted, since many of the
> effects of CR at the cellular level (e.g. decreased mitochondrial ROS
> production) can be attributed to phenomena that appear to have no genetic
> basis.
Hang on: What is your preferred interpretation of how CR decreases
mitochondrial ROS production? All the proposals I know of ARE based
on gene-expression changes.
Aubrey de Grey
