IUBio

Fountain of youth?

ufotruth at ix.netcom.com ufotruth at ix.netcom.com
Wed Jan 20 04:15:36 EST 1999


That abstract is very interesting indeed! I doubt it would be a
"fountain of youth" but it most probably has some therapeutic
possibilties!

Best Regards,
William



On 20 Jan 1999 08:49:53 GMT, Doug Skrecky <oberon at vcn.bc.ca> wrote:

>Authors
>  Shirahata S.  Kabayama S.  Nakano M.  Miura T.  Kusumoto K.  Gotoh M. 
>  Hayashi H.  Otsubo K.  Morisawa S.  Katakura Y.
>Institution
>  Institute of Cellular Regulation Technology, Graduate School of Genetic
>  Resources Technology, Kyushu University, Fukuoka, Japan.
>Title
>  Electrolyzed-reduced water scavenges active
>  oxygen species and protects DNA from oxidative damage.
>Source
>  Biochemical & Biophysical Research Communications.  234(1):269-74, 1997 May
>  8.
>Abstract
>  Active oxygen species or free radicals are considered to cause extensive
>  oxidative damage to biological macromolecules, which brings about a variety
>  of diseases as well as aging. The ideal scavenger for active oxygen should be
>  'active hydrogen'. 'Active hydrogen' can be produced in reduced
>  water near the cathode during electrolysis of
>  water. Reduced water exhibits high pH, low
>  dissolved oxygen (DO), extremely high dissolved molecular hydrogen (DH), and
>  extremely negative redox potential (RP) values. Strongly
>  electrolyzed-reduced water, as well as
>  ascorbic acid, (+)-catechin and tannic acid, completely scavenged O.-2
>  produced by the hypoxanthine-xanthine oxidase (HX-XOD) system in sodium
>  phosphate buffer (pH 7.0). The superoxide dismutase (SOD)-like activity of
>  reduced water is stable at 4 degrees C for over a month and
>  was not lost even after neutralization, repeated freezing and melting,
>  deflation with sonication, vigorous mixing, boiling, repeated filtration, or
>  closed autoclaving, but was lost by opened autoclaving or by closed
>  autoclaving in the presence of tungsten trioxide which efficiently adsorbs
>  active atomic hydrogen. Water bubbled with hydrogen gas
>  exhibited low DO, extremely high DH and extremely low RP values, as does
>  reduced water, but it has no SOD-like activity. These
>  results suggest that the SOD-like activity of reduced water
>  is not due to the dissolved molecular hydrogen but due to the dissolved
>  atomic hydrogen (active hydrogen). Although SOD accumulated H2O2 when added
>  to the HX-XOD system, reduced water decreased the amount of
>  H2O2 produced by XOD. Reduced water, as well as catalase and
>  ascorbic acid, could directly scavenge H2O2. Reduce water
>  suppresses single-strand breakage of DNA b active oxygen species produced by
>  the Cu(II)-catalyzed oxidation of ascorbic acid in a dose-dependent manner,
>  suggesting that reduced water can scavenge not only O2.- and
>  H2O2, but also 1O2 and .OH.





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