So your saying that telomere length is only initially important and changing
it later doesn't have any significant impact?
Magnus Lynch wrote in message <36A1DBDF.61AF89F6 at cam.ac.uk>...
>Is possible that the
>length of the telomeres is detected at the beginning of development by some
>as yet unidentified mechanism and then 'remembered' by the cell throughout
>the lifetime of the animal. The cell would then enter replicative senesence
>when the telomeres had shortened by a specific amount. It is clear that if
>this mechanism is correct than absolute telomere length would be irrelevant
>and although the telomeres of telomerase knock out mice shortened by an
>absolute amount every generation the cell would still enter senescence
after
>the same time.