On 7 Apr 1999 02:20:40 GMT, excelife at earthlink.net (Thomas Mahoney)
wrote:
>It is of interest that the paper; (J Cell Biol 1999 Feb 22;144(4):589-601.
>"Telomere Length Dynamics and Chromosomal Instability in Cells Derived from
>Telomerase Null Mice.", Hande MP, et al), indicates that "At various points
>during the growth of the immortal mTER-/- cells, telomere length was
>stabilized in a chromosome-specific manner.", and shows that some mouse cells
>can become immortalized in the absence of telomerase or it's catalytic
>component mTR.
I have a simple question. What does mTER-/- mean? Does it mean
mouse telomerase something-or-other? What does the -/- mean?
thanks
