In article <jrg8.521.0011583D at cornell.edu>, jrg8 at cornell.edu writes:
>>> Is anyone familiar with Galvin Greenoak's studies from which he
> contends that "feeding time" (I call it chronoprandiology) is relevant to
> longevity in that his animals fed equivalent calories showed significant
> differences in aging parameters with the only dietary difference being
> control group was ad lib. while intervention group received food only
> between 8-12 am. ? What is particularly interesting to me about this
> is the concept that so many of the calorie restriction studies were
> done with a "one-meal-per-day" protocol (? anyone familiar with
> others that spread the limited calories around?). I'm familiar with
> the "alternate-day feeding" protocol... but it strikes me now that
> it may be possible to arrive at a reasonable ("do-able") diet for
> humans with moderate calorie restriction (say less 20%) and modified
> fasting (eating only betw 8-12 am) to arrive at the benefits associated
> with more typical CR protocols (30-40% calories). Has anyone tried this...
> longterm...???....on humans..????
Yes there are some humans attempting precisely this. Check out the
CR-society mailing list. However it is more doable to restrict eating
to the evening meal. One can even justify this by noting that the
rodents are nocturnal creatures, so that their morning meal comes at
the end of their active period. On a more practical level, it is simple
enough for most people to skip breakfast and either skip or have a
very light lunch. But it is hard to have a morning meal (which awakens
the appetite) and then go for the rest of the day without eating.
Ian H