Hayflick limit.

Duane Hewitt duane at IMMORTALITY.ORG
Sun Dec 15 10:50:37 EST 1996

The Hayflick limit refers to a phenomenon that occurs when human cells
are grown in tissue culture. Under these conditions it is observed that
the population can only double a limited number of times (around 50)
before the cells senesce and are unable to grow any more. It is
named after noted biogerontologist Leonard Hayflick. 

The Hayflick limit varies amongst different cells and depends
mainly on their physiological age.

Fetal cells can divide 50 +/-10 times. However cells from patients
afflicted with "accelerated aging" syndromes such as Werners syndrome
or Progeria are not capable of dividing as many times as cells from
normal individuals who are the same chronological age. The number of
times cells can divide decreases with age.

Duane Hewitt

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