In article <Pine.A32.3.91.951116193716.23952H-100000 at barbados.cc.odu.edu>,
rcd100x at barbados.cc.odu.edu wrote:
>> Is the crystal structure of telomerase known? I've done an extensive
> literature search and so far have not come across any xray
> crystallography studies on this protein.
>> If anyone knows of an article that has reported telomerase's crystal
> structure, please email the bibliographic information to me.
>> Thanks in advance.
>> Raechelle Clarin-Yballe
>rcd100x at barbados.cc.odu.edu.us> Department of Chemistry and Biochemistry
> Old Dominion University
> Norfolk, Virginia
Telomerase has only recently been cloned in Tetrahymena, none of the
mammalian enzymes have been cloned (at least none that have been publicly
announced). I don't know the progress on making crystals of Tetrahymena
telomerase, but I would bet it is still a while off.
Marc Lamphier
Univ. of Tokyo