"Programmed" .vs. cumulative damage causes of cell-cycle failure

Johann JOETS joets at hermes.univ-poitiers.fr
Tue Nov 14 15:19:51 EST 1995

In article <JITpwAfNBh107h at chambers.ak.planet.co.nz>, steve at chambers.ak.planet.co.nz (Steve Chambers) says:

>Besides which, an immortalised cell line quickly loses it's resemblance
>to the cell type from which it arose - in other words it's damaged, or
>"aged" might be a better word ;-)
Immortalised cell line are often in a less differenciated state than parental. 
So "younger"...
If they become immortal, they stop to age ! (it's a damage too -) )
Then it raises the idea that cells are able to "decide" to not age and to respond to time assaults.
So why aging ? for evolution ? ( are bacteria able to age ?)

Johann JOETS
Institut de Biologie Moleculaire et d'Ingenierie Genetique
Laboratoire de Genetique Physiologique et Moleculaire
Universite de Poitiers
40, Av du Recteur Pineau, 86 022 Poitiers
TEL : 49 45 38 64
FAX : 49 45 35 03

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