I am looking forward to any information towards structural aspects
or biochemical activity changes of Glyceraldehyde-3(?)-phosphate-
dehydrogenase or its derivative enzymes that are involved in muscular
activities in the heart. Has there been any work on any conformational
changes or loss of activity of this enzyme in heart-patients? I
strongly presume that there is. There are a few thousand papers on the
structure of this enzyme from various sources, but I did not come
across any that is obtained from heart patients.
Barani
