There have been several messages about the enzyne telomerase. This
enzyme consists of an RNA fragment as well as a very large protein. The
RNA fragment has been identified and the relevant DNA cloned.
However the protein portion of this enzyme has not been purified
at all. Moreover, while a good enzyme assay is available, it seems to
be the case that it is not an easy assay because often the enzyme is
present in very small amounts. Because the enzyme has not been purified
there is no possibility at the moment of achieving the molecular cloning
of the cDNA or of the gene.
It is clear however that this enzyme is of tremendous interest.
Sydney
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Sydney SHALL,
Laboratory of Cell and Molecular Biology,
Biology Building,
University of Sussex,
Brighton,
East Sussex BN1 9QG,
ENGLAND.
Telephone: +44.273.67.83.03
FAX: +44.273.67.84.33
E-Mail:
Janet: S.Shall at uk.ac.sussex
Elsewhere: S.Shall at sussex.ac.uk
EARN/BITNET: S.Shall%sussex at ukacrl
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