Apoptosis and glutathione

Padmakumar Narayanan narayana at vet.vet.purdue.edu
Fri Mar 18 15:39:01 EST 1994

Dear nettors,
I recently came across articles in NATURE and CELL that stated that a decreased
glutathione level and an increased lipid peroxidation activity was associated
with apoptosis in thymocytes. They also stated that the increased lipid peroxidation was not associated with the NADPH Oxidase complex in the plasma membrane.
Can an increased mitochondrial respiratory activity lead to this phenomenon.
Any thoughts about it? 
Padma kumar narayanan
purdue cytometry labs
purdue university
w. lafayette

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