Malcolm McMahon cuhes at csv.warwick.ac.uk
Thu Jun 2 04:56:59 EST 1994

In article <9405301043.AA17560 at pclsp2>,
	vinz at PCLSP2.KUICR.KYOTO-U.AC.JP (Vincenzo Nardi-Dei) writes:
>Normal cells, should not develop in cancer-like form even when
>their clock is not terminated; cells are inhibited in the growth
>by the contact with the surrounding cells. This contact makes the cell
>to "understand" its position and role in the organism. When for some
>mutation the information on the contact inhibition is lost in the
>cell, it could become cancer-like.

The idea is that the death clock is a second line of defence against cancer.
That to be a "success" and cancerous mutation must overcome both the normal
controls on growth and the death clock. This would enourmously decrease the
likelyhood of any given mutation being dangerous.


More information about the Ageing mailing list

Send comments to us at biosci-help [At] net.bio.net