VERPHELD at VTVM1.CC.VT.EDU wrote:
: Autoimmune prone MRL/lpr mice have been reported to have deffective Fas genes
: which would presumably alter the negative selection process in the thymus. I
: would like to know if anybody has any thoughtson why this deffective fas gene w
: ould alter T cell development and yet have no effect on other developmental
: processes mediatred through apoptosis.
: ************************************************************************
: Daniela I. Verthelyi
: Virgina Tech.
: USA
:VERPHERLD at VTVM1
Could there be many ways to start the "program" of apoptosis? If this is
the case, could fas be T-cell/T-cell precursor specific?
Trei