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cell division and ageing

Sydney Shall bafa1 at central.sussex.ac.uk
Fri Jun 4 11:56:44 EST 1993


Recent discusion has touched upon the question as to whether cell division
is related
to human ageing.  The answer is clearly that cell division is related 
to human ageing.  There is some indirect evidence for this statement; 
but there is direct evidence 
in the human genetic condition known as Werner's Syndrome.  
In this condition, there is severe premature ageing and the life-span 
is approximately halved.  Cells from these patients show a much 
reduced (between 3 and 5 fold) ability to proliferate, thus it 
is now clear that there is some, currently unclear connection between 
cell proliferation and human ageing.

    Sydney Shall


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Sydney SHALL,
Laboratory of Cell and Molecular Biology,
Biology Building,
University of Sussex,
Brighton,
East Sussex BN1 9QG,
ENGLAND.

Telephone: +44.273.67.83.03

FAX: +44.273.67.83.33

E-Mail:

	Janet:		BAFA1 at uk.ac.sussex.central

	Elsewhere:	BAFA1 at central.sussex.ac.uk

	EARN/BITNET:	BAFA1%sussex.central at ukacrl


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