Vuaghn Gehle has offered a possible explanation for the long-lived C.
elegans mutant that Cynthia Kenyon et al have recently described. I
wonder if there is supporting data indicating the damaging effects of
oxygen radicals in those cases where SOD or another enzyme is thought
to be defective. I have in mind increased protein damage and
particularly increased DNA damage. I wonder how much of an increase
in oxygen radicals cells (or organisms) can meet without displaying
(a) signs of increased damage and (b) lethality.
Sydney SHALL
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Sydney SHALL,
Laboratory of Cell and Molecular Biology,
Biology Building,
University of Sussex,
Brighton,
East Sussex BN1 9QG,
ENGLAND.
Telephone: +44.273.67.83.03
FAX: +44.273.67.84.33
E-Mail:
Janet: S.Shall at uk.ac.sussex
Elsewhere: S.Shall at sussex.ac.uk
EARN/BITNET: S.Shall%sussex at ukacrl
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