Dysdifferentiation

[John Warren]

I remember reading some book on ageing where the author mentions the notion
of _dysdifferentiation_. That is, many of the problems that cells encounter
during ageing is a manifestation of the cells undergoing a loss of their
differentiated states (i.e., going back to an almost undifferentiated state).
Has anyone heard anything recently about this concept? Also, does anyone know
of any ways to artificially dysdifferentiate a cell?

-John Warren
 jwarren at gold.ucs.indiana.edu
 JWARREN at IUBACS